In order to solve the single machine scheduling problem, and improve the reliability and stability of the equipment, a single machine scheduling model considering piecewise linear deterioration and maintenance unavailability time was established according to the characteristics of continuous fault detection and discrete fault detection. Based on the system reliability theory, the single machine scheduling problem considering machine reliability was studied, and the advantages and disadvantages of maintenance strategy were compared by unified processing of decision conditions. The influence of related parameter changes on production scheduling optimization was determined by single factor and two factor adjustment analysis. The results show that the solution time of the model increases exponentially with the decreasing direction of unit delay cost, and the greater the unit delay cost, the faster the solution speed. The change of delay cost per unit time will not cause a significant change in maintenance cost, and the cost function does not have jumping nodes in flexible periodic maintenance, so it can not be adjusted adaptively. Ratio of preventive maintenance time to fault minor maintenance time has great influence on maintenance decision under discrete detection. The unified processing method of decision conditions can reduce the calculation time and detection cost, and better solve the problems of excessive maintenance or insufficient maintenance in discrete fault detection. These will help to reduce operating costs and improve economic benefits.