The pervaporation membrane techology was adopted to recover isopropanol used in the production process of ceftriaxone of CSPC, and it was compared with the original salt extraction process. The dehydration performance of the pervaporation membrane was tested to provide basic data for industrial design. The result showed with isopropanol that water content of no more than 1% could be recovered from isopropanol with water content of 15% by the pervaporation membrane techology, and the handling capacity is 6000kg/d. For the superiority of low energy consumption and low pollution, the pervaporation membrane process could be used to replace the salt extraction process.