The experiment used PSB-MBR to degenerate the VB₁₂ wastewater. After the enablement and the movement of the reactor, we have analyzed some affecting factors such as the aeration quantity, hydraulic detention time, the viability of the strain, the COD concentration in water entry and so on. When the hydraulic detention time is 35h, the experiment temperature is at 30℃, the pH value of the wastewater is 6～8, and the dissolved oxygen is within 0.5～1.0mg/L, the degradation rate of COD can reach 90%.