This paper introduces the contrast coagulation experiment of different coagulation conditions of Wuhu Shangxintang civil waste water, the interaction of the flocculation effect factors is discussed.The result shows that the interaction of the flocculation factors to turbid remove exists certain synergistic effect.When tested at 20℃,pH= 7.5～8.4,PAC-PAM co-use disposal of waste water, the total reagent to be added is 80mg for every liter waste water, and the optimized weight proportion of reagent component is V(PAC)∶V(PAM)=8∶2,the turbid remove efficient being 93.18%.